Direct electrophysiological recordings of neural activity from the brain are crucial for understanding the mechanisms underlying cognition. While a great body of knowledge has been gained from direct recordings in animal models, many functions are uniquely human or do not have an equivalent animal model.  These include speech, volition, recall, imagery, dreams and others.  Most human studies rely on non-invasive techniques which are limited by their spatial or temporal resolutions. Some clinical procedures provide a unique opportunity in which neural activity can be recorded directly from the human brain with spatial and temporal resolutions that are comparable to those used in animal models. These rare clinical opportunities offer a window to brain mechanisms at the level of single neuron activity and local field potentials. In addition, they offer opportunity for precise electrical stimulation of neuronal circuits. The current 2-day symposium will bring leading researchers in the field of intracranial electrophysiology, to discuss their latest research and provide their insights from inside the human brain.

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